Forgotten stars Daniel Kerr and Chad Cornes have been named in their respective teams to play their first games for 2011 in Saturday's clash between Port Adelaide and West Coast at AAMI Stadium.
West Coast premiership midfielder and 2007 All Australian Kerr hasn't played since Round 4, 2010 after tearing three hamstring ligaments off the bone while Cornes, twice an All Australian, missed the final eight games of last year with a finger injury and was overlooked for Round 1.
It will be Cornes' first match under new Port Adelaide coach Matthew Primus, replacing Jay Schulz, who has a knee injury.
Kerr is one of three inclusions for the Eagles with Nic Naitanui and Patrick McGinnity coming in for injured duo Mark LeCras and Chris Masten and the omitted Ashton Hams.
St Kilda will hand Daniel Archer his AFL debut on Friday night against Richmond at the MCG. Archer, from Tasmania, is a key forward who was elevated off the rookie list for Michael Gardiner last week and was preferred to Justin Koschitzke, who is yet to prove he is fit again after off-season ankle surgery. Andrew McQualter is the omitted player.
Richmond have made just one change from the side which was beaten by Carlton by 20 points in the season opener. Hard-nut Jake King returns from suspension at the expense of the suspended Alex Rance.
North Melbourne regain three important players for Saturday's clash with Collingwood at Etihad Stadium. Drew Petrie comes back from suspension while Todd Goldstein and Nathan Grima are back from injury. Ben Warren, Ben McKinley and Cameron Pederson miss out. Collingwood have made no change.
Gold Coast will take close to their best side into their first AFL match against Carlton on Saturday night at the Gabba in a line-up which features 12 debutants. Carlton have made one change, dropping Kane Lucas for first-gamer Matthew Watson.
Geelong regain a trio of vital players for Saturday's trip to Perth to take on the Dockers, with Cameron Ling, Paul Chapman and James Podsiadly all included, while Joel Selwood has been named despite being knocked out against St Kilda last week. Youngster Cameron Guthrie and Daniel Menzel make way while Matthew Scarlett is suspended. Fremantle have brought in Matt De Boer for the omitted Jayden Pitt.
Western Bulldogs father-son selection Mitch Wallis gets another shot at his AFL debut, named on an extended bench for Sunday's match against Brisbane alongside Will Minson, Jordan Roughead and Brodie Moles. Easton Wood (ankle) is the only omission at the moment.
Brisbane have named two possible debutants in Jared Polec and Broc McCauley, along with veteran Luke Power, who has overcome a back injury and Tom Collier and Matt Maguire in their extended team after losing Jonathan Brown and Brent Staker to serious injuries.
Angus Monfries (general soreness) will miss Essendon's trip to Sydney to take on the Swans, with livewire Alwyn Davey, who has recovered from his broken arm, Kyle Reimers, Tom Bellchambers and Brent Prismall all included on an extended bench.
Sydney may give Luke Parker his AFL debut, with the Swans' second round selection at last year's draft named as one of four inclusions along with Brett Meredith, Craig Bird and Mike Pyke. Mark Seaby is left out.
Hawthorn skipper Luke Hodge will be given every chance to prove he is ready for his return from an Achilles injury in Sunday's match against Melbourne. Hodge will train on Saturday and has been named as one of three inclusions into the 25, with Xavier Ellis and Brent Guerra.
Melbourne regain key defender James Frawley, who is likely to get the job on Lance Franklin, while Jake Spencer and Matthew Warnock are included on the bench.