It all kicks off on Friday night when Collingwood hosts the Brisbane Lions at Marvel Stadium in the top-of-the-table clash.
Richmond meets North Melbourne in a day of celebration as Trent Cotchin, Jack Riewoldt and Jack Ziebell bid farewell, before St Kilda and Geelong clash in a very significant match on Saturday night.
Melbourne v Hawthorn and Fremantle v Port Adelaide make it a very interesting Sunday.
Who wins this weekend?
Check out the tips from our SEN experts:
Dwayne Russell
Running tally: 136
Brisbane
Richmond
Carlton
GWS
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
Garry Lyon
Running tally: 130
Collingwood
Richmond
Carlton
GWS
Geelong
Sydney
Western Bulldogs
Melbourne
Port Adelaide
Gerard Whateley
Running tally: 125
Brisbane
Richmond
Carlton
GWS
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
Gareth Hall
Running tally: 124
Brisbane
Richmond
Gold Coast
GWS
Geelong
Adelaide
Western Bulldogs
Hawthorn
Fremantle
Andy Maher
Running tally: 124
Brisbane
Richmond
Carlton
GWS
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
Sam Edmund
Running tally: 123
Brisbane
Richmond
Carlton
GWS
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
Tim Watson
Running tally: 123
Brisbane
Richmond
Carlton
Essendon
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
Campbell Brown
Running tally: 117
Collingwood
Richmond
Carlton
GWS
St Kilda
Adelaide
Western Bulldogs
Melbourne
Fremantle
Andrew Gaze
Running tally: 114
Brisbane
Richmond
Carlton
GWS
Geelong
Adelaide
Western Bulldogs
Melbourne
Port Adelaide
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