The teams are in for the weekend and Carlton fans are rejoicing with the news Sam Walsh will take on Adelaide.
The reigning Gary Ayres Medallist missed the first month of the season with back issues, but will face the Crows.
Geelong and St Kilda will both unveil debutants as Connor O'Sullivan and Hugo Garcia are named.
Big names in Ollie Wines, Liam Baker and Marcus Windhager return, while North Melbourne has made the call to drop Jaidyn Stephenson and the Bulldogs have omitted Caleb Daniel.
See all the team changes for AFL Round 5 below!
Melbourne versus Brisbane
Melbourne
IN: K. Tholstrup
OUT: K. Pickett (suspended)
Brisbane
UNCHANGED
Essendon versus Western Bulldogs
Essendon
IN: S.Durham, A.Davey Jnr
OUT: W.Setterfield (Injured), A.Perkins (Injured)
Western Bulldogs
IN: J.O'Donnell
OUT: C. Daniel
GWS Giants versus St Kilda
GWS Giants
UNCHANGED
St Kilda
IN: M.Windhager, H.Garcia
OUT: A.Hastie (Omitted), Z.Jones (Omitted)
Carlton versus Adelaide
Carlton
IN: S. Walsh
OUT: L. Fogarty (suspension)
Adelaide
IN: W.Hamill, L.Gollant
OUT: P.Parnell (Injured), C.Burgess (Omitted)
Gold Coast versus Hawthorn
Gold Coast
UNCHANGED
Hawthorn
UNCHANGED
Port Adelaide versus Fremantle
Port Adelaide
IN: O.Wines, S.Powell-Pepper
OUT: T.Boak (Injured), J.Finlayson (Suspension)
Fremantle
IN: N. Erasmus
OUT: M.Frederick (Injured)
Geelong versus North Melbourne
Geelong
IN: C.O'Sullivan
OUT: J.Kolodjashnij (Managed)
North Melbourne
IN: B.Nyuon, T.Sellers, C.Lazzaro, B.Drury
OUT: C.Zurhaar (Injured), J.Stephenson (Omitted), K.Dawson (Injured), L.Shiels (Injured)
West Coast versus Richmond
West Coast
IN: T.Brockman
OUT: L.Rawlinson (Omitted)
Richmond
IN: L.Baker, H.Ralphsmith
OUT: J.Ross (Injured), T.Taranto (Injured)